top of page

CrampiOra - Herbal Support for Menstrual Comfort

nivira-wellness-crampiora-nutraceutical-menstrual-period-cramp-comfort-formula-supplement.

SCIENTIFIC BACKGROUND OF INGREDIENTS
The publications listed below are peer-reviewed scientific articles cited for reference and informational purposes only.

 

Zingiber officinale (Ginger) 

Ginger is one of the most extensively researched botanicals in women’s health.

  • Evaluated in multiple randomized clinical trials for menstrual discomfort

  • Systematic reviews and meta-analyses suggest ginger may support pain modulation and inflammatory balance during menstruation

  • Studied both alone and in comparison with conventional analgesics

 

Foeniculum vulgare (Fennel) 

Fennel has a long history of traditional use for menstrual and digestive comfort.

  • Clinical trials and meta-analyses have evaluated fennel for its role in supporting menstrual comfort

  • Research suggests antispasmodic and smooth-muscle–relaxing properties

Cinnamomum verum (Cinnamon) 

Cinnamon has been studied for its anti-inflammatory and antispasmodic properties.

  • Included in clinical trials and systematic reviews evaluating herbal approaches to primary dysmenorrhea

  • Often studied in combination with other botanicals such as ginger and fennel

Boswellia serrata (Salai) 

Boswellia is known for its role in inflammatory pathway modulation.

  • Clinical and observational studies have evaluated Boswellia for pain management and inflammatory balance

  • Recent research has explored its use in women experiencing menstrual discomfort

The referenced studies evaluate individual ingredients. This specific product has not been clinically evaluated.

 

Scientific References

 

Randomized Clinical Trials

  1. The effect of mefenamic acid and ginger on pain relief in primary dysmenorrhea. Link:https://pubmed.ncbi.nlm.nih.gov/25399316/ (https://link.springer.com/article/10.1007/s00404-014-3548-2

  2. Effect of Zingiber officinale rhizomes on pain relief in primary dysmenorrhea: A placebo-controlled randomized trial. 
    Link:https://pubmed.ncbi.nlm.nih.gov/22781186/ (https://link.springer.com/article/10.1186/1472-6882-12-92)

 

Systematic Reviews & Meta-Analyses

  1. Efficacy of herbal medicine (cinnamon, fennel, ginger) for primary dysmenorrhea: A systematic review and meta-analysis of randomized controlled trials. 
    Link:https://pubmed.ncbi.nlm.nih.gov/32603204/ (https://journals.sagepub.com/doi/10.1177/0300060520936179

  2. Efficacy of ginger in the treatment of primary dysmenorrhea: A systematic review and meta-analysis. 
    Link: https://pubmed.ncbi.nlm.nih.gov/33842121/
    (https://www.cureus.com/articles/52509-efficacy-of-ginger-in-the-treatment-of-primary-dysmenorrhea-a-systematic-review-and-meta-analysis#!/

  3. Fennel for reducing pain in primary dysmenorrhea: A systematic review and meta-analysis of randomized controlled trials.
    Link: https://pubmed.ncbi.nlm.nih.gov/33182553/ 
    (https://www.mdpi.com/2072-6643/12/11/3438)

  4. Efficacy of ginger for alleviating the symptoms of primary dysmenorrhea: A systematic review and meta-analysis of randomized clinical trials. 
    Link: https://pubmed.ncbi.nlm.nih.gov/26177393/
    (https://academic.oup.com/painmedicine/article-abstract/16/12/2243/2460294?redirectedFrom=fulltext&login=false

  5. Effect of fennel on primary dysmenorrhea: A systematic review and meta-analysis. Journal of Complementary and Integrative Medicine.
    Link: https://pubmed.ncbi.nlm.nih.gov/34187122/
    (https://www.degruyterbrill.com/document/doi/10.1515/jcim-2019-0212/html

Observational & Complementary Research

  1. Acmella oleracea and Boswellia serrata for symptom relief and reduced analgesic use in women with dysmenorrhea.
    Link: https://pubmed.ncbi.nlm.nih.gov/40642179/
    (https://journals.sagepub.com/doi/10.1089/whr.2025.0056)

Regulatory Disclaimer

The statements presented above have not been reviewed or evaluated by the Food Safety and Standards Authority of India (FSSAI) or any other regulatory authority. The information provided is for educational purposes only. This product is not intended for the diagnosis, treatment, cure, or prevention of any disease.

bottom of page